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Tcf3tm4.1Cmu
Targeted Allele Detail
Nomenclature
Symbol: Tcf3tm4.1Cmu
Name: transcription factor 3; targeted mutation 4.1, Cornelis Murre
MGI ID: MGI:4366005
Synonyms: Tcfe2adeltaE47
Gene: Tcf3  Location: Chr10:80409514-80433647 bp, - strand  Genetic Position: Chr10, 39.72 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:153423
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Germline, cre mediated recombination removed the E47 isoform-specific exon and the neo cassette. (J:153423)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tcf3 Mutation:  25 strains or lines available
References
Original:  J:153423 Beck K, et al., Distinct roles for E12 and E47 in B cell specification and the sequential rearrangement of immunoglobulin light chain loci. J Exp Med. 2009 Sep 28;206(10):2271-84
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory