Heyl^tm1.1Abmu
Targeted Allele Detail

Summary

• Symbol: Heyl^tm1.1Abmu
• Name: hairy/enhancer-of-split related with YRPW motif-like; targeted mutation 1.1, Abhishek Mukhopadhyay
• MGI ID: MGI:4365753
• Synonyms: HeyL^fx
• Gene: Heyl Location: Chr4:123127349-123143663 bp, + strand Genetic Position: Chr4, 57.41 cM
• Alliance: Heyl^tm1.1Abmu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:153555
• Parent Cell Line: HM-1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd-Hprt1^b-m3

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an frt flaned neo cassette with a 3' loxP site was inserted downstream of exon 5. Germ line, flp mediated recombination removed the neo cassette leaving exons 2 through 5 floxed. (J:153555)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Heyl Mutation: 21 strains or lines available

References

• Original: J:153555 Mukhopadhyay A, et al., HeyL regulates the number of TrkC neurons in dorsal root ganglia. Dev Biol. 2009 Oct 1;334(1):142-51
• All: 1 reference(s)