Tg(Tagln-cre)1Zli
Transgene Detail

Summary

• Symbol: Tg(Tagln-cre)1Zli
• Name: transgene insertion 1, Zhenlin Li
• MGI ID: MGI:4365411
• Synonyms: SM22-Cre
• Transgene: Tg(Tagln-cre)1Zli Location: unknown
• Alliance: Tg(Tagln-cre)1Zli page

Transgene origin

• Strain of Origin: C57BL/6 or DBA/2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Tagln-cre)1Zli expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tagln (MGI:106012)

• Mutation details: Expression of nuclear-localized Cre recombinase is driven by the promoter region of the mouse tagln gene, including 2126 bp of 5' flanking sequence, the first exon, the first intron and the first 15 bp of the second intron with the last four nucleotides modified from CATG to GCTT to remove the initiation codon. In transgenic mice, Cre is expressed initially in the heart and somites and later in the arteries of the vascular system, but not in the visceral muscles nor in the veins. (J:34770, J:82809)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tagln (mouse) Summary of all recombinase alleles driven by Tagln. Alliance mouse Tagln gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

According to Zhenlin Li, donor of mice bearing this transgene to the European Mouse Mutant Archive (EMMA), it was generated in a "C57BL6/DBA2" genetic background.

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 4 reference(s)