Gnb2tm1(KOMP)Wtsi
Targeted Allele Detail
|
Symbol: |
Gnb2tm1(KOMP)Wtsi |
Name: |
guanine nucleotide binding protein (G protein), beta 2; targeted mutation 1, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:4364786 |
Gene: |
Gnb2 Location: Chr5:137526389-137531772 bp, - strand Genetic Position: Chr5, 76.54 cM
|
IMPC: |
Gnb2 gene page |
|
Mutant Cell Lines: |
EPD0272_5_D03, EPD0272_5_D04 |
Germline Transmission: |
Unknown
|
Parent Cell Line: |
JM8A1.N3 (ES Cell)
|
Strain of Origin: |
C57BL/6N-Atm1Brd
|
Project Collection: |
KOMP-CSD
|
|
Allele Type: |
|
Targeted (Null/knockout, Reporter) |
Mutations: |
|
Insertion, Intragenic deletion
Vector: L1L2_Bact_P
|
|
|
Mutation details: The insertion of the L1L2_Bact_P cassette created a deletion of size 2377 starting at position 137526362 and ending at position 137528739 of Chromosome 5 (Genome Build GRCm39). This deletion results in the removal of functionally critical exon(s). The cassette is composed of an FRT site followed by lacZ sequence and a loxP site. This first loxP site is followed by a neomycin resistance gene under the control of the human beta-actin promoter, SV40 polyA, a second FRT site and a second loxP site.
(J:148605, J:173534)
|
|
|
|
Original: |
J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009; |
All: |
2 reference(s) |
|