About   Help   FAQ
Csrp2bptm1a(KOMP)Wtsi
Targeted Allele Detail
Nomenclature
Symbol: Csrp2bptm1a(KOMP)Wtsi
Name: cysteine and glycine-rich protein 2 binding protein; targeted mutation 1a, Wellcome Trust Sanger Institute
MGI ID: MGI:4363521
Gene: Csrp2bp  Location: Chr2:144368983-144407676 bp, + strand  Genetic Position: Chr2, 71.01 cM
Mutation
origin
Mutant Cell Lines:  EPD0025_4_A07, EPD0025_4_A09, EPD0025_4_B07, EPD0025_4_B08, EPD0025_4_B09, EPD0025_4_C07, EPD0025_4_C08, EPD0025_4_C09, EPD0025_4_D08, EPD0025_4_D09, EPD0025_4_E09, EPD0025_4_F07, EPD0025_4_F08, EPD0025_4_G07, EPD0025_4_G08, EPD0025_4_G09, EPD0025_4_H07, EPD0025_4_H08, EPD0025_4_H09 (Wellcome Trust Sanger Institute)
Germline Transmission:  Earliest citation of germline transmission: J:164007
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_gt1
 
Mutation detailsThe L1L2_gt1 cassette was inserted at position 144375403 of Chromosome 2 upstream of the critical exon(s) (Build GRCm38). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 144376193. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. If cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other KOMP alleles can be found at http://www.knockoutmouse.org/aboutkompstrategies. (J:148605, J:173534)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Csrp2bp Mutation:  60 strains or lines available
References
Original:  J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009;
All:  8 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/21/2017
MGI 6.08
The Jackson Laboratory