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Zfp184tm1a(KOMP)Wtsi
Targeted Allele Detail
Nomenclature
Symbol: Zfp184tm1a(KOMP)Wtsi
Name: zinc finger protein 184 (Kruppel-like); targeted mutation 1a, Wellcome Trust Sanger Institute
MGI ID: MGI:4362182
Gene: Zfp184  Location: Chr13:21945094-21960779 bp, + strand  Genetic Position: Chr13, 8.08 cM
Mutation
origin
Mutant Cell Lines:  EPD0016_3_A03, EPD0016_3_B03, EPD0016_3_C01, EPD0016_3_D02, EPD0016_3_E01, EPD0016_3_F01, EPD0016_3_F02, EPD0016_3_F03, EPD0016_3_G01, EPD0016_3_H03, EPD0017_3_A07, EPD0017_3_A08, EPD0017_3_B07, EPD0017_3_B08, EPD0017_3_C09, EPD0017_3_D08, EPD0017_3_D09, EPD0017_3_E07, EPD0017_3_E09, EPD0017_3_F07, EPD0017_3_F08, EPD0017_3_F09, EPD0017_3_H07, EPD0017_3_H09 (Wellcome Trust Sanger Institute)
Germline Transmission:  Earliest citation of germline transmission: J:204812
Parent Cell Line:  JM8 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: KOMP-CSD
Mutation
description
Allele Type:    Targeted (Conditional ready, Null/knockout, Reporter)
Mutation:    Insertion     Vector: L1L2_st1
 
Mutation detailsThe L1L2_st1 cassette was inserted at position 21946579 of Chromosome 13 upstream of the critical exon(s) (Build GRCm38). The cassette is composed of an FRT flanked lacZ/neomycin sequence followed by a loxP site. An additional loxP site is inserted downstream of the targeted exon(s) at position 21947334. The critical exon(s) is/are thus flanked by loxP sites. A "conditional ready" (floxed) allele can be created by flp recombinase expression in mice carrying this allele. Subsequent cre expression results in a knockout mouse. If cre expression occurs without flp expression, a reporter knockout mouse will be created. Further information on targeting strategies used for this and other KOMP alleles can be found at http://www.knockoutmouse.org/aboutkompstrategies. (J:148605, J:173534)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 1 line available
Carrying any Zfp184 Mutation:  12 strains or lines available
References
Original:  J:148605 Wellcome Trust Sanger Institute, Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2009;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory