Tg(Des-cre)1Zli
Transgene Detail

Summary

• Symbol: Tg(Des-cre)1Zli
• Name: transgene insertion 1, Zhenlin Li
• MGI ID: MGI:4362109
• Synonyms: Des-Cre
• Transgene: Tg(Des-cre)1Zli Location: unknown
• Alliance: Tg(Des-cre)1Zli page

Transgene origin

• Strain of Origin: C57BL/6 or DBA/2

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Des-cre)1Zli expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Des (MGI:94885)

• Mutation details: This transgene contains 4.6 kb of DNA from the mouse desmin gene (nucleotides -4005 to +608), including 5' regulatory sequences, the 5' untranslated region (UTR) and exon 1 through nucleotide +608, driving expression of Cre recombinase with a nuclear localization signal. This promoter has been shown to direct expression in the heart from embryonic day (E) 7.5 and in skeletal muscle and some vascular smooth muscle cells from E9.5. (J:65247, J:82809)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Des (mouse) Summary of all recombinase alleles driven by Des. Alliance mouse Des gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

According to Zhenlin Li, donor of mice bearing this transgene to the European Mouse Mutant Archive (EMMA), it was generated in a "C57BL6/DBA2" genetic background.

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 4 reference(s)