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Ins2tm1.1Mnt
Targeted Allele Detail
Nomenclature
Symbol: Ins2tm1.1Mnt
Name: insulin II; targeted mutation 1.1, Massimo Trucco
MGI ID: MGI:4361695
Synonyms: Ins2-
Gene: Ins2  Location: Chr7:142678656-142743381 bp, - strand  Genetic Position: Chr7, 88.0 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152798
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsMice expressing the Ins2tm1Mnt allele were crossed to Tg(EIIa-cre)C5379Lgmd mice to delete the Ins2 gene in the germline. (J:152798)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ins2 Mutation:  23 strains or lines available
References
Original:  J:152798 Fan Y, et al., Thymus-specific deletion of insulin induces autoimmune diabetes. EMBO J. 2009 Sep 16;28(18):2812-24
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory