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Targeted Allele Detail
Symbol: Ush1gtm1.1Ugds
Name: USH1 protein network component sans; targeted mutation 1.1, Unite de Genetique des Deficits Sensoriels
MGI ID: MGI:4361359
Synonyms: Ush1gfl
Gene: Ush1g  Location: Chr11:115315192-115322041 bp, - strand  Genetic Position: Chr11, 80.84 cM
Germline Transmission:  Earliest citation of germline transmission: J:171218
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S1/SvImJ
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA loxP site was inserted upstream of exon 2 and a loxP site and FRT flanked neo cassette were inserted downstream of exon 2 via homologous recombination. Flp mediated recombination removed the neo cassette leaving exon 2 floxed. (J:171218)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ush1g Mutation:  13 strains or lines available
Original:  J:171218 Caberlotto E, et al., Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5825-30
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory