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Myo15tm1.1(cre)Ugds
Targeted Allele Detail
Nomenclature
Symbol: Myo15tm1.1(cre)Ugds
Name: myosin XV; targeted mutation 1.1, Unite de Genetique des Deficits Sensoriels
MGI ID: MGI:4361284
Synonyms: Myo15-cre
Gene: Myo15  Location: Chr11:60469339-60528369 bp, + strand  Genetic Position: Chr11, 37.81 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:171218
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S1/SvImJ
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Mutation detailsA cre gene and FRT flanked hygromycin cassette were inserted at the transcriptional start site. Flp mediated recombination removed the hygromycin cassette. (J:171218)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Myo15     Summary of all recombinase alleles driven by Myo15.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Myo15 Mutation:  87 strains or lines available
References
Original:  J:171218 Caberlotto E, et al., Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5825-30
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory