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Targeted Allele Detail
Symbol: Nfil3tm1.1Brad
Name: nuclear factor, interleukin 3, regulated; targeted mutation 1.1, Hugh Brady
MGI ID: MGI:4360908
Synonyms: E4bp4-
Gene: Nfil3  Location: Chr13:52967209-52981073 bp, - strand  Genetic Position: Chr13, 27.68 cM
Germline Transmission:  Earliest citation of germline transmission: J:152774
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsA loxP site was inserted upstream of the coding region and a floxed neo cassette was inserted downstream of the coding exon. Germ line, cre mediated recombination removes the neo cassette and coding exon. The absence of protein expression was confirmed by western blot analysis on heart extracts. (J:152774)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nfil3 Mutation:  5 strains or lines available
Original:  J:152774 Gascoyne DM, et al., The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development. Nat Immunol. 2009 Oct;10(10):1118-24
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
The Jackson Laboratory