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Tg(tetO-PLAGL2)P3Ysy
Transgene Detail
Nomenclature
Symbol: Tg(tetO-PLAGL2)P3Ysy
Name: transgene insertion P3, Yih-Sheng Yang
MGI ID: MGI:4360887
Synonyms: (tetO)7CMV-PLAGL2
Transgene: Tg(tetO-PLAGL2)P3Ysy  Location: unknown  
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(tetO-PLAGL2)P3Ysy expresses 1 gene
 
Mutation detailsA CMV promoter with 7 tetO sites was used to drive inducible the human cDNA. Four founders were generated (P1, P2, P3, and P4) with 4, 10, 26, and 180 copies of teh transgene, respectively. P3 was selected as the representative line. (J:152422)
Phenotypes
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Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:152422 Yang YS, et al., PLAGL2 expression-induced lung epithelium damages at bronchiolar alveolar duct junction in emphysema: bNip3- and SP-C-associated cell death/injury activity. Am J Physiol Lung Cell Mol Physiol. 2009 Sep;297(3):L455-66
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/24/2015
MGI 5.21
The Jackson Laboratory