Tg(Drd1-tdTomato)5Calak
Transgene Detail

Summary

• Symbol: Tg(Drd1-tdTomato)5Calak
• Name: transgene insertion 5, Nicole Calakos
• MGI ID: MGI:4360387
• Synonyms: Drd1a-tdTomato, Tg(Drd1a-tdTomato)5Calak
• Transgene: Tg(Drd1-tdTomato)5Calak Location: unknown
• Alliance: Tg(Drd1-tdTomato)5Calak page

Transgene origin

• Strain of Origin: (C57BL/6 x SJL)F1

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The cDNA for a modified DsRed fluorescent protein (designated as tdTomato) along with a synthetic bovine growth hormone polyadenylation signal was inserted into the Drd1a BAC clone RP23-47M2 by homologous recombination in E coli. The tdTomato cDNA replaced the ATG codon as well as an additional 180 bp of coding sequence. Six independent founder lines were established but only line 5 has been reported. (J:123053, J:132997)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:132997 Shuen JA, et al., Drd1a-tdTomato BAC transgenic mice for simultaneous visualization of medium spiny neurons in the direct and indirect pathways of the basal ganglia. J Neurosci. 2008 Mar 12;28(11):2681-5
• All: 59 reference(s)