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Klf15hlb444
Chemically induced Allele Detail
Nomenclature
Symbol: Klf15hlb444
Name: Kruppel-like factor 15; heart, lung and blood, 444
MGI ID: MGI:4359847
Synonyms: H340Y
Gene: Klf15  Location: Chr6:90439558-90452220 bp, + strand  
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU) (Null/knockout)
Mutation:    Single point mutation
 
Mutation detailsThis phenotypic mutant was identified in an ENU mutagenesis screen. The causative mutation is a C to T transition mutation at nucleotide position 1197 in the coding region of Krppel-like Factor 15 (Klf15), resulting in a missense mutation at amino acid 340 in the encoded protein. (J:280739)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Klf15 Mutation:  8 strains or lines available
References
Original:  J:77944 JAX National Heart, Lung and Blood Program for Genomic Applications (PGA), Heritable mouse mutants from the JAX NHLBI ENU Mutagenesis Program. MGI Direct Data Submission. 2002;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/23/2021
MGI 6.17
The Jackson Laboratory