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Kdm1btm1.1Tche
Targeted Allele Detail
Nomenclature
Symbol: Kdm1btm1.1Tche
Name: lysine (K)-specific demethylase 1B; targeted mutation 1.1, Taiping Chen
MGI ID: MGI:4359289
Synonyms: Aof11loxP
Gene: Kdm1b  Location: Chr13:47043499-47084613 bp, + strand  Genetic Position: Chr13, 24.5 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152382
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA floxed beta-Geo cassette was inserted in intron 16 and an additional loxP site was inserted in intron 13. Exons 14-16 are thus flanked by loxP sites. Mice were crossed with transgenic mice carrying an unspecified Zp3-cre transgene to excise exons 14-16 and the beta Geo cassette. (J:152382)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kdm1b Mutation:  45 strains or lines available
References
Original:  J:152382 Ciccone DN, et al., KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints. Nature. 2009 Sep 17;461(7262):415-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/14/2017
MGI 6.11
The Jackson Laboratory