Tg(BHLHE41*P385R)1Yfu
Transgene Detail

Summary

• Symbol: Tg(BHLHE41*P385R)1Yfu
• Name: transgene insertion 1 Ying-Hui Fu
• MGI ID: MGI:4356550
• Synonyms: hDEC2 P385R TG
• Transgene: Tg(BHLHE41*P385R)1Yfu Location: unknown
• Alliance: Tg(BHLHE41*P385R)1Yfu page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(BHLHE41*P385R)1Yfu expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  BHLHE41 (79365)

  Bhlhe41

  (MGI:1930704)

  Transgene codes for a protein with a proline to arginine mutation.

• Mutation details: A C to G transversion was created in BAC:RP11-288E19 from Children's Hospital Oakland Research Institute. This resulted in a proline to arginine change at codon 385 of the human BHLHE41. (J:151927)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:151927 He Y, et al., The transcriptional repressor DEC2 regulates sleep length in mammals. Science. 2009 Aug 14;325(5942):866-70
• All: 2 reference(s)