Tg(Mef2c-lacZ)5Blk
Transgene Detail

Summary

• Symbol: Tg(Mef2c-lacZ)5Blk
• Name: transgene insertion 5, Brian L Black
• MGI ID: MGI:4356545
• Synonyms: Mef2c - F10-44-lacZ
• Transgene: Tg(Mef2c-lacZ)5Blk Location: unknown
• Alliance: Tg(Mef2c-lacZ)5Blk page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: A 44 bp segment of the F10 fragment located in intron 5 of Mef2c and containing the FOX:ETS motif was used to direct expression of lacZ by the Hspa1b minimal promoter. Lac Z expression is specific to endothelial cells during early embryogenesis. Enhancer activity is extinguished after E10.5. (J:152218)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:152218 De Val S, et al., Combinatorial regulation of endothelial gene expression by ets and forkhead transcription factors. Cell. 2008 Dec 12;135(6):1053-64
• All: 1 reference(s)