Tg(Mef2c-lacZ)3Blk
Transgene Detail

Summary

• Symbol: Tg(Mef2c-lacZ)3Blk
• Name: transgene insertion 3, Brian L Black
• MGI ID: MGI:4356494
• Synonyms: Mef2c-L8-lacZ
• Transgene: Tg(Mef2c-lacZ)3Blk Location: unknown
• Alliance: Tg(Mef2c-lacZ)3Blk page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: Bacterial lacZ was inserted into the first coding exon (exon5) of Mef2c in BAC clone GS133 in such a way that the start codon was deleted but the exon boundaries were preserved. This transgenic reporter essentially recapitulates endogenous Mef2c expression in vivo. (J:152141)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:152141 Dodou E, et al., Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development. Development. 2004 Aug;131(16):3931-42
• All: 1 reference(s)