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Tg(Mef2c-lacZ)1Blk
Transgene Detail
Summary
Symbol: Tg(Mef2c-lacZ)1Blk
Name: transgene insertion 1, Brian L Black
MGI ID: MGI:4356310
Synonyms: Mef2c-AHF-lacZ, mef2c-F6/Frag2-LacZ, mef2c-F6-lacZ
Transgene: Tg(Mef2c-lacZ)1Blk  Location: unknown  
Alliance: Tg(Mef2c-lacZ)1Blk page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA 6142 bp segment located from 16.3-22.5 kb downstream of Mef2c exon 1 and 48.9-55.1 kb upstream of the first coding exon (exon 5) and including the non-coding exon 3, was used to direct lacZ expression using the Hspa1b minimal promoter. LacZ expression was restricted to the anterior heart field of embryos which includes pharyngeal mesoderm, the right ventricle, and the outflow tract. Expression is not observed in the adult. (J:152141)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:152141 Dodou E, et al., Mef2c is a direct transcriptional target of ISL1 and GATA factors in the anterior heart field during mouse embryonic development. Development. 2004 Aug;131(16):3931-42
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory