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Targeted Allele Detail
Symbol: Rfktm1.2Jcbr
Name: riboflavin kinase; targeted mutation 1.2, Jens C Bruning
MGI ID: MGI:4356070
Synonyms: RFKdelta
Gene: Rfk  Location: Chr19:17394043-17401349 bp, + strand  Genetic Position: Chr19, 12.82 cM, cytoband B
Germline Transmission:  Earliest citation of germline transmission: J:151999
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsMice carrying the floxed Rfktm1.1Jcbr allele were crossed with a cre-deleter strain to remove exons 1 and 2 from the germline. Removal of the exons was confirmed by genomic PCR. (J:151999)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rfk Mutation:  2 strains or lines available
Original:  J:151999 Yazdanpanah B, et al., Riboflavin kinase couples TNF receptor 1 to NADPH oxidase. Nature. 2009 Aug 27;460(7259):1159-63
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
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