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mt-Atp8m1
Spontaneous Allele Detail
Nomenclature
Symbol: mt-Atp8m1
Name: mitochondrially encoded ATP synthase 8; mutation 1
MGI ID: MGI:4355536
Synonyms: mt-Atp8FVB/NJ
Gene: mt-Atp8  Location: ChrMT:7766-7969 bp, + strand  Genetic Position: ChrMT, Syntenic
Mutation
origin
Strain of Origin:  FVB/NJ
Mutation
description
Allele Type:    Spontaneous
Mutation:    Single point mutation
 
Mutation detailsA G to T transversion is located at nucleotide 7778 resulting in an aspartic acid to tyrosine substitution in the fifth amino acid of the conserved N-terminus of the protein. This substitution has been reported in the FVB/NJ strain. (J:143901)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any mt-Atp8 Mutation:  4 strains or lines available
References
Original:  J:143901 Yu X, et al., Dissecting the effects of mtDNA variations on complex traits using mouse conplastic strains. Genome Res. 2009 Jan;19(1):159-65
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory