Tg(TcraA1,TcrbA1)1Alm
Transgene Detail
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| Symbol: |
Tg(TcraA1,TcrbA1)1Alm |
| Name: |
transgene insertion 1, Andrew Mellor |
| MGI ID: |
MGI:4354497 |
| Synonyms: |
A1, A1(M), A1 TCR-transgenic |
| Transgene: |
Tg(TcraA1,TcrbA1)1Alm Location: unknown
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| Alliance: |
Tg(TcraA1,TcrbA1)1Alm page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(TcraA1,TcrbA1)1Alm expresses
2 genes
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Mutation details: The TCR alpha- and beta-chain from the A1 CD41 T cell genomic clone that had been isolated from CBA/Ca mice was used to make constructs to generate transgenic mice. The A1 clone recognizes the minor histocompatibility Ag H-Y, which is present in male mice but absent in female mice, in the
context of H2-Ek.
(J:94036)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:94036 Zelenika D, et al., Rejection of H-Y disparate skin grafts by monospecific CD4+ Th1 and Th2 cells: no requirement for CD8+ T cells or B cells. J Immunol. 1998 Aug 15;161(4):1868-74 |
| All: |
24 reference(s) |
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