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Pax6tm1.1Ued
Targeted Allele Detail
Nomenclature
Symbol: Pax6tm1.1Ued
Name: paired box 6; targeted mutation 1.1, University of Edinburgh
MGI ID: MGI:4354123
Synonyms: Pax6loxPdelta
Gene: Pax6  Location: Chr2:105668900-105697364 bp, + strand  Genetic Position: Chr2, 55.31 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:151427
Parent Cell Line:  E14TG2a (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediated recombination removed exons 5, 5a, and 6. The absence of protein expression was confirmed by immunohistochemistry on brain sections. (J:151427)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pax6 Mutation:  47 strains or lines available
References
Original:  J:151427 Simpson TI, et al., Normal ventral telencephalic expression of Pax6 is required for normal development of thalamocortical axons in embryonic mice. Neural Dev. 2009;4:19
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory