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Mir96Dmdo
Chemically induced Allele Detail
Nomenclature
Symbol: Mir96Dmdo
Name: microRNA 96; diminuendo
MGI ID: MGI:4354110
Synonyms: DEA12, diminuendo, Dmdo
Gene: Mir96  Location: Chr6:30169446-30169551 bp, - strand  Genetic Position: Chr6, 12.52 cM
Mutation
origin
Strain of Origin:  C3HeB/FeJ
Mutation
description
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
 
Mutation detailsENU induces an A to T transversion in the seed region resulting in transcript destabilization and translational inhibition. An additional mutation (C to T) was identified in exon 5 of Akr1b10. However, it does not alter the codon and is not thought to cause the phenotype associated with this mutant. (J:151354)
Inheritance:    Semidominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mir96 Mutation:  3 strains or lines available
References
Original:  J:151354 Lewis MA, et al., An ENU-induced mutation of miR-96 associated with progressive hearing loss in mice. Nat Genet. 2009 May;41(5):614-8
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
03/21/2017
MGI 6.08
The Jackson Laboratory