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Cacna2d1tm1Aschw
Targeted Allele Detail
Nomenclature
Symbol: Cacna2d1tm1Aschw
Name: calcium channel, voltage-dependent, alpha2/delta subunit 1; targeted mutation 1, Arnold Schwartz
MGI ID: MGI:4353680
Synonyms: alpha-2/delta-1-, alpha2/delta-1-
Gene: Cacna2d1  Location: Chr5:15934788-16374504 bp, + strand  Genetic Position: Chr5, 6.56 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:151101
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsExon 2 was disrupted by insertion of a neomycin cassette. Gene inactivation was confirmed by no signal in immunoblot analysis of homozygote heart, brain and skeletal muscle extracts. (J:151101)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cacna2d1 Mutation:  32 strains or lines available
References
Original:  J:151101 Fuller-Bicer GA, et al., Targeted disruption of the voltage-dependent calcium channel alpha2/delta-1-subunit. Am J Physiol Heart Circ Physiol. 2009 Jul;297(1):H117-24
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/11/2017
MGI 6.10
The Jackson Laboratory