About   Help   FAQ
Targeted Allele Detail
Symbol: Nreptm1Wcw
Name: neuronal regeneration related protein; targeted mutation 1, William C Wetsel
MGI ID: MGI:4353245
Synonyms: P311-
Gene: Nrep  Location: Chr18:33437019-33464029 bp, - strand  Genetic Position: Chr18, 18.18 cM
Germline Transmission:  Earliest citation of germline transmission: J:151154
Parent Cell Line:  CJ7 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe third and part of the fourth exon were replaced with a neo cassette. The absence of transcript expression was confirmed by northern blot analysis on skeletal muscle extracts and by RT-PCR analysis on hippocampus and cerebellum extracts. (J:151154)
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nrep Mutation:  3 strains or lines available
Original:  J:151154 Taylor GA, et al., Behavioral characterization of P311 knockout mice. Genes Brain Behav. 2008 Oct;7(7):786-95
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.15
The Jackson Laboratory