Calcr^tm1Rda
Targeted Allele Detail

Summary

• Symbol: Calcr^tm1Rda
• Name: calcitonin receptor; targeted mutation 1, Rachel A Davey
• MGI ID: MGI:4352932
• Synonyms: CTR^flox
• Gene: Calcr Location: Chr6:3685680-3764714 bp, - strand Genetic Position: Chr6, 1.81 cM
• Alliance: Calcr^tm1Rda page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:150982
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 13 and a floxed neomycin cassette was inserted after the untranslated region encoded in exon 14. Correct targeting was confirmed by genomic PCR. (J:150982)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Calcr Mutation: 58 strains or lines available

References

• Original: J:150982 Davey RA, et al., Calcitonin receptor plays a physiological role to protect against hypercalcemia in mice. J Bone Miner Res. 2008 Aug;23(8):1182-93
• All: 3 reference(s)