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AspmGt(AJ0069)Wtsi
Gene trapped Allele Detail
Nomenclature
Symbol: AspmGt(AJ0069)Wtsi
Name: abnormal spindle microtubule assembly; gene trap AJ0069, Wellcome Trust Sanger Institute
MGI ID: MGI:4345389
Gene: Aspm  Location: Chr1:139454772-139494091 bp, + strand  Genetic Position: Chr1, 61.45 cM, cytoband F
Mutation
origin
Mutant Cell Line:  AJ0069
Germline Transmission:  Earliest citation of germline transmission: J:164424
Parent Cell Line:  E14TG2a.4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Sanger Inst. Gene Trap Res.
Mutation
description
Allele Type:    Gene trapped
Mutation:    Insertion of gene trap vector     Vector: pGT0lxr
 
Mutation detailsTrapped gene association determined by genome coordinate overlap and strand. The gene trap vector was determined to have integrated between exons 25 and 26 such that the predicted protein product only lacks the C-terminal amino acids encoded by the three 3' exons but retains the N-terminal microtubule-binding domain, the calponin homology domains, and the calmodulin-binding isoleucine-glutamine (IQ) repeats. (J:164424)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Aspm Mutation:  3 strains or lines available
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/12/2019
MGI 6.13
The Jackson Laboratory