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PcntGt(RRU388)Byg
Gene trapped Allele Detail
Nomenclature
Symbol: PcntGt(RRU388)Byg
Name: pericentrin (kendrin); gene trap RRU388, BayGenomics
MGI ID: MGI:4340776
Gene: Pcnt  Location: Chr10:76187097-76278620 bp, - strand  Genetic Position: Chr10, 38.8 cM
Mutation
origin
Mutant Cell Line:  RRU388
Germline Transmission:  Earliest citation of germline transmission: J:226309
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Gene trapped (Null/knockout, Reporter)
Mutation:    Insertion of gene trap vector     Vector: pGT0Lxf     Vector Type: gene trap
 
Mutation detailsA gene trap vector containing a splice-acceptor sequence upstream of the reporter gene, beta-geo (a fusion gene of beta-galactosidase and neomycin phosphotransferase II) inserted into intron 1. Immunoblot analysis showed a complete loss of the encoded protein in the lysates from whole embryos and immortalized MEFs. (J:226309)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 23 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pcnt Mutation:  120 strains or lines available
Notes
All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory