Irak1bp1^{Gt(OST277418)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Irak1bp1^{Gt(OST277418)Lex}
• Name: interleukin-1 receptor-associated kinase 1 binding protein 1; gene trap OST277418, Lexicon Genetics
• MGI ID: MGI:4260875
• Gene: Irak1bp1 Location: Chr9:82711859-82729741 bp, + strand Genetic Position: Chr9, 45.16 cM
• Alliance: Irak1bp1^{Gt(OST277418)Lex} page

Mutation origin

• Mutant Cell Line: OST277418
• Germline Transmission: Earliest citation of germline transmission: J:161380
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: Trapped gene association determined by genome coordinate overlap and strand. This gene was targeted with a retroviral integration of a splice acceptor site fused to neomycin resistance cassette and a poly-A sequence between the first and the second exon. This "gene-trapped" allele resulted in a complete loss of Irak1bp1 mRNA in mouse embryonic fibroblasts (MEFs) as measured by Northern blot analysis. (J:161380)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST277418	CG603176 ; (MGI Seq Detail)	3' RACE	Chr9:82719286-82728825 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  1 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Schematic of the Irak1bp1^{Gt(OST277418)Lex} allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Irak1bp1 Mutation: 11 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)