Rras2^{Gt(OST47398)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Rras2^{Gt(OST47398)Lex}
• Name: related RAS viral (r-ras) oncogene 2; gene trap OST47398, Lexicon Genetics
• MGI ID: MGI:4160490
• Gene: Rras2 Location: Chr7:113646017-113717016 bp, - strand Genetic Position: Chr7, 59.29 cM, cytoband F2
• Alliance: Rras2^{Gt(OST47398)Lex} page

Mutation origin

• Mutant Cell Line: OST47398
• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: Retroviral insertion occurred between coding exons 1 and 2 (NM_025846.1). RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. (J:82809)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST47398	CG502423 ; (MGI Seq Detail)	3' RACE	Chr7:113649605-113659655 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  23 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Rras2 Mutation: 31 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)