Enah^{Gt(RRG138)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Enah^{Gt(RRG138)Byg}
• Name: ENAH actin regulator; gene trap RRG138, BayGenomics
• MGI ID: MGI:4129025
• Synonyms: Mena^GT
• Gene: Enah Location: Chr1:181723949-181847555 bp, - strand Genetic Position: Chr1, 84.93 cM
• Alliance: Enah^{Gt(RRG138)Byg} page

Mutation origin

• Mutant Cell Line: RRG138
• Germline Transmission: Earliest citation of germline transmission: J:250072
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Hypomorph, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• Mutation details: A gene trap vector inserted into intron 2. The endogenous full-length protein is replaced by a fusion-protein encoded by the first two Mena exons and the reporter gene. However, a low amount of endogenous full length 140 kDa isoform protein is found in brain. but not other tissues where the gene is normally expressed. (J:250072)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRG138	CC325907 ; (MGI Seq Detail)	5' RACE	Chr1:181789321-181847161 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  253 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Enah Mutation: 208 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)