Rest^{Gt(RRC160)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Rest^{Gt(RRC160)Byg}
• Name: RE1-silencing transcription factor; gene trap RRC160, BayGenomics
• MGI ID: MGI:4127119
• Gene: Rest Location: Chr5:77413338-77434279 bp, + strand Genetic Position: Chr5, 41.61 cM

Mutation origin

• Mutant Cell Line: RRC160
• Germline Transmission: Unknown
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• Mutation details: A B-gal neo cassette was inserted within intron 3. ES Cells contained lower levels of transcript (52%) and reduced abundance of full length protein. Trapped gene association determined by genome coordinate overlap and strand. (J:163999)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRC160	CC200280 ; (MGI Seq Detail)	5' RACE	Chr5:77423077-77423160 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  128 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rest Mutation: 92 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)