Mark4^Gt(XG191)Byg
Gene trapped Allele Detail

Summary

• Symbol: Mark4^Gt(XG191)Byg
• Name: MAP/microtubule affinity regulating kinase 4; gene trap XG191, BayGenomics
• MGI ID: MGI:4125782
• Gene: Mark4 Location: Chr7:19158700-19192746 bp, - strand Genetic Position: Chr7, 9.78 cM
• Alliance: Mark4^Gt(XG191)Byg page

Smaller lipid droplets in the brown adipose tissue of Mark4^Gt(XG191)Byg/Mark4^Gt(XG191)Byg mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: XG191
• Germline Transmission: Earliest citation of germline transmission: J:192469
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• Mutation details: The gene trap vector inserted into exon 8. Western blot analysis confirmed the absence of protein expression in the fat and muscle. (J:192469)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XG191	CC182925 ; (MGI Seq Detail)	5' RACE	Chr7:19170863-19179091 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  3 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Generation of the Mark4^Gt(XG191)Byg allele

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mark4 Mutation: 34 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 6 reference(s)