Commd9^{Gt(AQ0362)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Commd9^{Gt(AQ0362)Wtsi}
• Name: COMM domain containing 9; gene trap AQ0362, Wellcome Trust Sanger Institute
• MGI ID: MGI:3864158
• Gene: Commd9 Location: Chr2:101716607-101731984 bp, + strand Genetic Position: Chr2, 54.07 cM
• Alliance: Commd9^{Gt(AQ0362)Wtsi} page

Neural tube edema, hemorrhages, and hypoplastic hearts in Commd9^{Gt(AQ0362)Wtsi}/Commd9^{Gt(AQ0362)Wtsi} embryos

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: AQ0362
• Germline Transmission: Earliest citation of germline transmission: J:230747
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxr
• Mutation details: A gene trap vector containing the beta-geo cassette was inserted between exons 5 and 6. Immunoblot analysis confirmed the complete absence of protein expression in mouse embryonic fibroblasts derived from homozygous mutant embryos. (J:230747)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  AQ0362	CZ259006 ; (MGI Seq Detail)	5' RACE	Chr2:101716601-101716663 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  2 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Generation of the Commd9^{Gt(AQ0362)Wtsi} allele

Expression

In Structures Affected by this Mutation:

11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Commd9 Mutation: 49 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)