Mllt6^{Gt(AC0433)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Mllt6^{Gt(AC0433)Wtsi}
• Name: myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6; gene trap AC0433, Wellcome Trust Sanger Institute
• MGI ID: MGI:3856248
• Synonyms: Af17^-
• Gene: Mllt6 Location: Chr11:97554240-97576289 bp, + strand Genetic Position: Chr11, 61.05 cM
• Alliance: Mllt6^{Gt(AC0433)Wtsi} page

Mutation origin

• Mutant Cell Line: AC0433
• Germline Transmission: Earliest citation of germline transmission: J:169020
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxr
• Mutation details: The gene trap vector inserted into intron 7. The absence of protein expression was confirmed by western blot analysis on kidney, brain, and heart extracts. (J:169020)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  AC0433	CW988924 ; (MGI Seq Detail)	5' RACE	Chr11:97560347-97560461 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  99 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Generation of the Mllt6^{Gt(AC0433)Wtsi} allele

Expression

In Mice Carrying this Mutation:

103 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mllt6 Mutation: 142 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)