Efna3^tm1Ebp
Targeted Allele Detail

Summary

• Symbol: Efna3^tm1Ebp
• Name: ephrin A3; targeted mutation 1, Elena B Pasquale
• MGI ID: MGI:3852474
• Gene: Efna3 Location: Chr3:89221206-89230272 bp, - strand Genetic Position: Chr3, 39.06 cM
• Alliance: Efna3^tm1Ebp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:150784
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A cassette containing a floxed EYFP and frt flanked neo cassette was inserted into exon 1 in frame with the translation initiation site. Expression of the EYFP fusion protein was confirmed by western blot analysis and immunohistochemistry. (J:150784)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Efna3 Mutation: 10 strains or lines available

References

• Original: J:150784 Carmona MA, et al., Glial ephrin-A3 regulates hippocampal dendritic spine morphology and glutamate transport. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12524-9
• All: 4 reference(s)