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Targeted Allele Detail
Symbol: Efna3tm1Ebp
Name: ephrin A3; targeted mutation 1, Elena B Pasquale
MGI ID: MGI:3852474
Gene: Efna3  Location: Chr3:89313899-89322939 bp, - strand  Genetic Position: Chr3, 39.06 cM
Germline Transmission:  Earliest citation of germline transmission: J:150784
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
Mutation detailsA cassette containing a floxed EYFP and frt flanked neo cassette was inserted into exon 1 in frame with the translation initiation site. Expression of the EYFP fusion protein was confirmed by western blot analysis and immunohistochemistry. (J:150784)
View phenotypes and curated references for all genotypes (concatenated display).
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Efna3 Mutation:  2 strains or lines available
Original:  J:150784 Carmona MA, et al., Glial ephrin-A3 regulates hippocampal dendritic spine morphology and glutamate transport. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12524-9
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
The Jackson Laboratory