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Et(cre/ERT2)2007Rdav
Transgene Detail
Nomenclature
Symbol: Et(cre/ERT2)2007Rdav
Name: enhancer trap 2007, Ron Davis
MGI ID: MGI:3852336
Transgene: Et(cre/ERT2)2007Rdav  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6J
Project Collection: Neuroscience Blueprint cre
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsAn enhancer trap transgenic approach was used to generate these mice. The hsyn-bgi-cre:ERT2-bGHpA transgene was designed with the human synapsin minimal promoter (hsyn) minimal promoter driving a cre-ERT2 fusion gene (cre recombinase fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand binding domain).A beta globin intron separates the promoter from the cre gene and the bovine growth hormone polyadenylation signal follows the cre sequence. This transgene was injected into C57BL/6J embryos. Founder line 2007 was established on a C57BL/6J genetic background. (J:150856)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Et(cre/ERT2)2007Rdav     Summary of all recombinase alleles driven by Et(cre/ERT2)2007Rdav. Comparative matrix view of recombinase activities
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:150856 Davis R, Large-scale enhancer trap project to generate transgenic cre alleles by Ron Davis at Baylor University. MGI Direct Data Submission. 2009;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory