About   Help   FAQ
Et(cre/ERT2)278Rdav
Transgene Detail
Nomenclature
Symbol: Et(cre/ERT2)278Rdav
Name: enhancer trap 278, Ron Davis
MGI ID: MGI:3852325
Transgene: Et(cre/ERT2)278Rdav  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6J
Project Collection: Neuroscience Blueprint cre
Transgene
description
Transgene Type:    Transgenic (Inducible, Recombinase)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsAn enhancer trap transgenic approach was used to generate these mice. The TK-bgi-cre:ERT2-bGHpA transgene was designed with the thymidine kinase (TK) minimal promoter driving a cre-ERT2 fusion gene (cre recombinase fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand binding domain). A beta globin intron separates the promoter from the cre gene and the bovine growth hormone polyadenylation signal follows the cre sequence. This transgene was injected into C57BL/6J embryos. Founder line 278 was established on a C57BL/6J genetic background. (J:150856)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Et(cre/ERT2)278Rdav     Summary of all recombinase alleles driven by Et(cre/ERT2)278Rdav. Comparative matrix view of recombinase activities
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:150856 Davis R, Large-scale enhancer trap project to generate transgenic cre alleles by Ron Davis at Baylor University. MGI Direct Data Submission. 2009;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/15/2020
MGI 6.15
The Jackson Laboratory