Tg(Slc6a3-icre)1Fto
Transgene Detail

Summary

• Symbol: Tg(Slc6a3-icre)1Fto
• Name: transgene insertion 1, Francois Tronche
• MGI ID: MGI:3852083
• Synonyms: BAC-DATiCre, DATcre, Tg(BAC-DATicrefto), Tg(Slc6a3-cre)1Fto
• Transgene: Tg(Slc6a3-icre)1Fto Location: unknown
• Alliance: Tg(Slc6a3-icre)1Fto page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Slc6a3-icre)1Fto expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Slc6a3 (MGI:94862)

• Mutation details: The nls-iCre ORF was introduced into the mouse dopamine transporter gene (Slc6a3) within the RP24408F13 BAC by homologous recombination in bacteria. A 177 kb DNA-fragment was injected into FVB/N oocytes. Two lines were generated. (J:129459, J:150544)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Slc6a3 (mouse) Summary of all recombinase alleles driven by Slc6a3. Comparative matrix view of recombinase activities Alliance mouse Slc6a3 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:129459 Turiault M, et al., Analysis of dopamine transporter gene expression pattern -- generation of DAT-iCre transgenic mice. FEBS J. 2007 Jul;274(14):3568-77
• All: 25 reference(s)