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Tg(AAVS1)A1Xob
Transgene Detail
Nomenclature
Symbol: Tg(AAVS1)A1Xob
Name: transgene insertion A1, Xandra Breakefield
MGI ID: MGI:3852016
Synonyms: AAVS1 transgenic mice (founder line A1)
Transgene: Tg(AAVS1)A1Xob  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x C3H)F1
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Mutation detailsAn 8.2 kb human genomic fragment containing the entire adeno-associated virus integration site 1 (AAVS1) locus was isolated after EcoRI digestion of plasmid pRIA-N3. Transgenic founder line A1 was established and found to have approximately 5 copies of the transgene integrated at a single locus. (J:150852)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:150852 Bakowska JC, et al., Targeted transgene integration into transgenic mouse fibroblasts carrying the full-length human AAVS1 locus mediated by HSV/AAV rep(+) hybrid amplicon vector. Gene Ther. 2003 Sep;10(19):1691-702
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/30/2021
MGI 6.17
The Jackson Laboratory