About   Help   FAQ
Tg(Cd8a-cre)1Itan
Transgene Detail
Nomenclature
Symbol: Tg(Cd8a-cre)1Itan
Name: transgene insertion 1, Ichiro Taniuchi
MGI ID: MGI:3851193
Synonyms: E8I-Cre
Transgene: Tg(Cd8a-cre)1Itan  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Mutation detailsThe 1.6 kb core of the E8I Cd8 locus enhancer region was inserted in front of the Cd8a promoter, and cre recombinase cDNA and an IRES-GFP-polyA cassette were inserted after the promoter to generated the transgene construct. (J:141009)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Cd8a     Summary of all recombinase alleles driven by Cd8a.
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:141009 Maekawa Y, et al., Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity. Nat Immunol. 2008 Oct;9(10):1140-7
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
01/14/2020
MGI 6.14
The Jackson Laboratory