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Foxp2tm2.2Woen
Targeted Allele Detail
Nomenclature
Symbol: Foxp2tm2.2Woen
Name: forkhead box P2; targeted mutation 2.2, Wolfgang Enard
MGI ID: MGI:3851108
Synonyms: Foxp2ko
Gene: Foxp2  Location: Chr6:14901388-15441201 bp, + strand  Genetic Position: Chr6, 6.49 cM, cytoband A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:150425
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediated recombination removed exon 7. The absence of protein expression was confirmed by western blot analysis on embryo extracts. (J:150425)
Phenotypes
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View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Foxp2 Mutation:  28 strains or lines available
References
Original:  J:150425 Enard W, et al., A humanized version of Foxp2 affects cortico-basal ganglia circuits in mice. Cell. 2009 May 29;137(5):961-71
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory