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Tg(GFAP-luc,GAPDH-rluc)172.9Mes
Transgene Detail
Nomenclature
Symbol: Tg(GFAP-luc,GAPDH-rluc)172.9Mes
Name: transgene insertion 172.9, Albee Messing
MGI ID: MGI:3850718
Synonyms: Dual-Glo, GFAP-fluc and GADPH-Rluc, GFAP-luc and GADPH-Rluc, Tg172-9
Transgene: Tg(GFAP-luc,GAPDH-rluc)172.9Mes  Location: unknown  
Transgene
origin
Strain of Origin:  (FVB x C57BL/6)F1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsTwo transgenic constructs were co-injected into fertilized oocytes. The first construct (GFAP-fLuc) included the firefly luciferase gene under the control of the 2.2kb human GFAP, glial fibrillary acidic protein promoter. The other construct (GAPDH-RLuc) consisted of the Renilla luciferase gene under the control of the 0.5kb human GAPDH, glyceraldehyde-3-phosphate dehydrogenase promoter. Founder line 172.9 was subsequently established. (J:150335)
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:150335 Cho W, et al., Dual transgenic reporter mice as a tool for monitoring expression of glial fibrillary acidic protein. J Neurochem. 2009 Jul;110(1):343-51
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/06/2021
MGI 6.16
The Jackson Laboratory