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Rhebtm1Pfw
Targeted Allele Detail
Nomenclature
Symbol: Rhebtm1Pfw
Name: Ras homolog enriched in brain; targeted mutation 1, Paul Worley
MGI ID: MGI:3850507
Synonyms: Rheb1f, Rhebfl
Gene: Rheb  Location: Chr5:24802823-24842361 bp, - strand  Genetic Position: Chr5, 11.93 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:150108
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 3 and an FRT flanked PGK-neo cassette and second loxP site were inserted downstream of exon 3 via homologous recombination. (J:150108, J:168571)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rheb Mutation:  23 strains or lines available
References
Original:  J:150108 Delgoffe GM, et al., The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment. Immunity. 2009 Jun 19;30(6):832-44
All:  16 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
09/10/2019
MGI 6.14
The Jackson Laboratory