About   Help   FAQ
Chemically induced Allele Detail
Symbol: Mycbp2m274-4Tpo
Name: MYC binding protein 2; mutation 274-4, Timothy P O'Brien
MGI ID: MGI:3849603
Synonyms: Phr274-4
Gene: Mycbp2  Location: Chr14:103113411-103346814 bp, - strand  Genetic Position: Chr14, 51.79 cM
Small size of Mycbp2m274-4Tpo/Mycbp2m274-4Tpo mice at birth

Show the 1 phenotype image(s) involving this allele.

Strain of Origin:  SSL/LeJ
Allele Type:    Chemically induced (ENU)
Mutation:    Single point mutation
Mutation detailsENU mutagenesis induced a T to A transversion at position 2599 in exon 15. This point mutation results in termination of protein translation instead of coding for a cystein at position 772 (C772X). The protein product is truncated after the second RCC1 homology domain. (J:149893)
Inheritance:    Recessive
Schematic of the ENU-induced Mycbp2m274-4Tpo mutation
View phenotypes for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mycbp2 Mutation:  96 strains or lines available
Strain of origin for this mutation was determined by its close linkage to Ednrbs (J:149893).

Original:  J:149893 Hagarman JA, et al., An essential gene mutagenesis screen across the highly conserved piebald deletion region of mouse chromosome 14. Genesis. 2009 Jun;47(6):392-403
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.03
The Jackson Laboratory