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P2ry14tm1Gbtm
Targeted Allele Detail
Nomenclature
Symbol: P2ry14tm1Gbtm
Name: purinergic receptor P2Y, G-protein coupled, 14; targeted mutation 1, Gary B T Moore
MGI ID: MGI:3849078
Synonyms: GPR105 null
Gene: P2ry14  Location: Chr3:59114623-59153492 bp, - strand  Genetic Position: Chr3, 28.96 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:149708
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was replaced with a lacZ and neo cassette. The absence of transcript expression was confirmed by RT-PCR on brain, lung, and esophagus extracts. (J:149708)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any P2ry14 Mutation:  4 strains or lines available
References
Original:  J:149708 Bassil AK, et al., UDP-glucose modulates gastric function through P2Y14 receptor-dependent and -independent mechanisms. Am J Physiol Gastrointest Liver Physiol. 2009 Apr;296(4):G923-30
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2020
MGI 6.15
The Jackson Laboratory