Fgfrl1^tm1.1Ptew
Targeted Allele Detail

Summary

• Symbol: Fgfrl1^tm1.1Ptew
• Name: fibroblast growth factor receptor-like 1; targeted mutation 1.1, Pascal te Welscher
• MGI ID: MGI:3849002
• Gene: Fgfrl1 Location: Chr5:108842051-108854816 bp, + strand Genetic Position: Chr5, 53.24 cM, cytoband E3-F
• Alliance: Fgfrl1^tm1.1Ptew page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149673
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line cre mediation removed exons 3 through 7. The absence of transcript expression was confirmed by RT-PCR on E12.5 embryo extracts. (J:149673)

Disease models

Expression

In Structures Affected by this Mutation:

30 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fgfrl1 Mutation: 28 strains or lines available

References

• Original: J:149673 Catela C, et al., Multiple congenital malformations of Wolf-Hirschhorn syndrome are recapitulated in Fgfrl1 null mice. Dis Model Mech. 2009 May-Jun;2(5-6):283-94
• All: 2 reference(s)