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Prdx4tm1.1Jufu
Targeted Allele Detail
Nomenclature
Symbol: Prdx4tm1.1Jufu
Name: peroxiredoxin 4; targeted mutation 1.1, Junichi Fujii
MGI ID: MGI:3848347
Synonyms: Prx4-
Gene: Prdx4  Location: ChrX:155323918-155340754 bp, - strand  Genetic Position: ChrX, 72.38 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:149074
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsGerm line, cre mediated recombination removed exon 1. The absence of protein expression was confirmed by western blot analysis on pancreas, spleen, kidney, large intestine, and testis of male mice. (J:149074)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prdx4 Mutation:  6 strains or lines available
References
Original:  J:149074 Iuchi Y, et al., Peroxiredoxin 4 knockout results in elevated spermatogenic cell death via oxidative stress. Biochem J. 2009 Apr 1;419(1):149-58
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory