Tg(Six2-GFP/cre)1Amc
Transgene Detail

Summary

• Symbol: Tg(Six2-GFP/cre)1Amc
• Name: transgene insertion 1, Andrew P McMahon
• MGI ID: MGI:3848345
• Synonyms: Six2-GC, Six2-GFPcre, Six2-GFP::Cre^Tg, Six2TGC
• Transgene: Tg(Six2-GFP/cre)1Amc Location: unknown
• Alliance: Tg(Six2-GFP/cre)1Amc page

Transgene origin

• Strain of Origin: Not Applicable

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Six2-GFP/cre)1Amc expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Six2

• Mutation details: In this transgene, the Six2 promoter drives a fusion protein of GFP and Cre recombinase. The transgene was randomly inserted into the genome. GFPCre is expressed transiently in renal epithelial precursors during the developmental period of active nephrogenesis. No GFPCre expression is present in the adult, and no expression is observed after injury. (J:148456)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Six2 (species not specified) Summary of all recombinase alleles driven by Six2. Comparative matrix view of recombinase activities

Expression

In Mice Carrying this Mutation:

90 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:122521 Park JS, et al., Wnt/{beta}-catenin signaling regulates nephron induction during mouse kidney development. Development. 2007 Jul;134(13):2533-9
• All: 17 reference(s)